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10.1126/science.1115360 Science 97 KretzO.FesterL.WehrenbergU.ZhouL.BrauckmannS.ZhaoS.et al (2004)

Ruiz JM, Blumwald E

Consistent with these findings, using a group of individuals with affective disorders including individuals with bipolar I, in either a manic or depressive episode, individuals with schizoaffective disorder bipolar type, and those with recurrent MDD, Ozcan et al

It also normalized intestinal permeability, restored cortical BDNF to control levels and significantly improved behavioral parameters in PTSD-model male mice, confirming probiotic efficacy via MGBA modulation

A deeper understanding of microbial-disease pathways could lead to more targeted treatments, the researchers wrote in their study, published today (June 24) in the journal Science Translational Medicine