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Another study demonstrated that MBP and the number of myelinating oligodendrocytes were decreased in 6-month old triple transgenic mice (3xTg-AD), the number of immature oligodendrocytes remained unchanged and mature non-myelinating cells were increased [29]

In the present study, a similar trend was observed

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Changing the parental feed also affected the embryonic gene expression of immune-, lipid transport-, and apolipoprotein genes [48], which leads to a domino effect of subsequent altered events through development

The mechanism of HSCT-mediated arrest of the brain inflammation in X-ALD is unclear