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This creates a neurogenic inflammatory response that can spread to surrounding skin
Activation of the Nrf2/HO-1 pathway restores N-acetylcysteine-induced impairment of the hypothalamus-pituitary-adrenal axis negative feedback by up-regulating GR expression and down-regulating GR expression into pituitary glands

[DOI] [PMC free article] [PubMed] [Google Scholar] 205.Xu, J

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