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Description
Chaperone-mediated autophagy in aging and disease

CONCLUSIONS Prevention trials of whole foods or simple extracts offer prospects for reducing an expanding global burden of cancer effectively with minimal cost, in contrast to promising isolated phytochemicals or pharmaceuticals 82

The regulation of apoptosis involves various factors, including BCl-2, which acts as an anti-apoptotic protein, helping to maintain the integrity of the mitochondrial membrane by binding to receptors on the outer mitochondrial membrane

Nascimento, E

Overall, our work shows the potential of therapeutically targeting ferroptosis in HR-NB and demonstrates both the feasibility and the challenges of including ferroptosis-inducing agents as part of a clinically relevant treatment protocol
