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Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands

GHK-Cu (Copper Tripeptide) Originally discovered in human plasma, GHK-Cu promotes collagen and elastin synthesis, supports DNA repair, and exhibits strong antioxidant effects

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Its extended half-life makes it valuable for studies requiring sustained IGF-1 activity in cellular repair, anti-aging, and body composition

Rubinek T, Rubinfeld H, Hadani M, Barkai G, Shimon I