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doi: 10.1177/0960327118774902

It is known that UV radiation can hyper activate the melanocytes through different ways including the regulation of melatonin-stimulating hormone receptors (MSHR), also known as Melanocortin-1 receptor (MC-1R), which can induce hormone binding and enhanced endogenous protein kinase A (PKA) and tyrosine kinase expression which can in turn lead to the phosphorylation of cAMP and control of melanogenesis that can induce higher melanin production

Related B Vitamins and Methylation Frequently Asked Questions (FAQ) About MTHFR: What is the MTHFR gene, and what does it do

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Asojo OA, Ceccarelli C (2014) Structure of glutathione S-transferase 1 from the major human hookworm parasite necatoramericanus (Na-GST-1) in complex with glutathione