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In rare cases, a genetic condition may limit the bodys ability to produce glutathione

Gupta S, Tyagi S, Almeida DV, Maiga MC, Ammerman NC, Bishai WR

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For example, age- and disease-related downregulation of the miRNA biogenesis pathway in adult neurons reportedly can lead to changes in their survival, functions, and connectivity (68)

Not only can a deficiency in vitamin B12 cause schizophrenia, but vitamins B6 and B9 can also contribute to the condition, and symptoms can be reduced by supplementing these vitamins alongside antipsychotics (70)