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Too much signal and the doseresponse curve flattens - you spend more money and expose yourself to more side effects for no extra benefit

And alcohol throws a wrench right into the middle of it

Wiest R, Lawson M, Geuking M

Dryad Digital Repository (2017) Acknowledgements The work was financially supported by Academy of Finland funded projects SCART (grant no
In contrast to PDGF-BB, in diabetic wounds, induced by alloxan application, BPC 157 largely promoted mature collagen in granulation tissue (Seveljevic-Jaran et al., 2006) (note, previously, BPC 157 healed alloxan-induced gastric lesions in rats (Petek et al., 1999))
