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AX, administered orally at a dose of 100 mg/kg per day, via feeding tube, using a medium-chain triglyceride-based preparation, starting one week before immobilization and throughout the treatment period, resulted in a reduction in the decline in FCSA (muscle fiber cross-sectional area), indicating a protective effect against immobilization-induced atrophy [23]

MOTS-c is a 16-amino acid peptide encoded from 12S rRNA region of the mitochondrial DNA [1]

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10.3390/biology11060935 39 DuffyC.PridgenW