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Furthermore, a meta-analysis encompassing 13 studies comprising 1,606 females diagnosed with PCOS revealed that sustained administration of metformin leads to a notable decrease in miscarriage and preterm birth rates, alongside an increase in full-term pregnancies
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[PubMed 237403] 1477

12 Moreover, much of the prior knowledge regarding HIF signaling has been generated from malignant tissue

In this review, we synthesize the pivotal factors and underlying mechanisms contributing to SGN degeneration
