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NNMT is an enzyme expressed in adipose tissue, the liver, and other tissues

This means you need proportionally higher doses via nasal spray to achieve similar systemic peptide levels

This mechanism is critical because neurons have a limited ability to synthesize endogenous GS (Dringen and Arend, 2025)

Patients on GLP-1 medications who want to maximize fat metabolism and support liver function Patients with mild weight loss goals (10-20 pounds) who prefer a lighter-touch approach Anyone seeking an energy boost even without active weight loss goals Patients concerned about liver health, particularly those with fatty liver disease Patients on hormone replacement therapy optimizing body composition Patients experiencing fatigue, brain fog, or low energy Timeline for Results Most patients notice increased energy within the first 1-2 injections, often within a day or two of their first dose

So why are there multiple B vitamins