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26, 101235 (2019), Abstract A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C
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doi: 10.1016/j.jpeds.2012.11.089 128 ClarkRHBloomBTSpitzerARGerstmannDR

There is evidence that these compounds can restore the sensitivity of cancer cells to both radio- and chemotherapy [128, 129]

Inhibiting NNMT with 5-Amino-1MQ preserves intracellular NAD+ levels, which supports mitochondrial function and has been shown in rodent models to reduce adiposity and improve insulin sensitivity