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Description
In trials where semaglutide was added on to basal insulin with or without metformin, severe hypoglycemia (requiring the assistance of another person) was reported in 1.5% of semaglutide-treated patients
It targets multiple pathways including inflammation, collagen synthesis, vascular repair, and tissue regeneration
Both GLP-1 and GH peptides affect glucose metabolism, requiring monitoring
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The NADase CD38 is involved in the immune response by producing second messengers ADPR, 20-deoxy-ADPR (2dADPR), NAADP, and cADPR
