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For TJA, priority endpoints include wound complications, prolonged drainage, hematoma requiring intervention, early readmission, and PJI, with follow-up sufficient to capture early revision risk

However, certain populations are at higher risk of deficiency: Adults over 50 (reduced absorption capacity) Individuals following vegan or strict vegetarian diets Those with gastrointestinal conditions such as Crohns disease or celiac disease Individuals taking long-term acid-reducing medications (PPIs, H blockers) When oral supplementation is insufficient or absorption is compromised, vitamin B12 shots deliver the nutrient directly into the bloodstream, bypassing the digestive system entirely

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Collagen Peptides: Backed by growing evidence for improving joint integrity, tendon resilience, and skin health making them a well-researched alternative to experimental recovery peptides