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doi: 10.1016/j.cell.2008.12.044
Mechanism: Multi-System Weight Loss Semaglutide is a modified analog of human GLP-1, the incretin hormone released by intestinal L-cells after eating
Retatrutide clinical trial results The phase 2 trial, published in the New England Journal of Medicine, tested retatrutide at doses ranging from 1 mg to 12 mg weekly in adults with obesity
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They work by targeting fat metabolism, particularly in the liver where fat deposits can accumulate
