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However, SH-SY5Y cells differed from Glioblastoma U251 cells, in: (a) being more sensitive (decreased in viability) to free copper or PA but as sensitive to Cu-PA co-treatment and (b) the level of generated ROS post Cu-PA treatment was not remarkably different from Cu or PA treated cells

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This review provides an up-to-date and integrative overview of current evidence regarding ASTs mechanisms of action across experimental and preclinical models of neurodegenerative diseases such as Alzheimers, Parkinsons, and Huntingtons diseases

As stated, this is a key difference of REDOXS from all other GLN trials