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In a recent double-blind, controlled study, the extent of coronary atherosclerosis was assessed with cardiac computed tomography angiography in 72 individuals (55 at study completion) at high risk of coronary heart disease randomized to receive either 2,400 mg of aged garlic extract or placebo for 52 weeks (98)

Abstract Cysteine catabolism in mammals is dependent upon cysteine dioxygenase (CDO), an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid (3-sulfinoalanine)

Visceral abdominal fat that doesn't respond to diet and exercise, metabolic syndrome risk factors, body composition goals focused on the midsection, and patients who want to address deep belly fat specifically rather than overall weight loss

10.1038/nn1106-1351 143

Using chemical inhibitors to block GCLC in animals leads to inconsistent and incomplete loss of GSH across tissues 19