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As a small molecule, it is resistant to digestive degradation, easily absorbed through the intestinal wall (79% bioavailability), and can be manufactured using conventional chemical synthesis at a fraction of the cost of peptide production

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However, further research using animal models is needed to evaluate the potential of B12 as an epidrug for in vivo modulation of peripheral biomarkers associated with persistent VCD in long COVID and to determine whether this contributes to neuroprotection

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