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doi: 10.1111/j.1346-8138.1985.tb02862.x

2021 Feb;9(1):100298

Structurally, C/EBP contains two unique transactivation domains (TAD1 and TAD2) near the N-terminus, as well as a transcriptional repressor domain, the basic leucine zipper region (bZIP), near the C-terminus

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Although intervention studies have partially indicated that the long-term consumption of dietary choline sources does not cause significant changes in plasma TMAO levels and there is no correlation between diets high in choline and CVD, observational studies do not support these findings