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Description
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2 Step 2: Acetaldehyde Acetate Aldehyde dehydrogenase (ALDH2) detoxifies acetaldehyde to acetate
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It also modulates oxidative stress via the nuclear factor 2 related to erythroid 2 (Nrf2) pathway, a transcription factor that controls the expression of numerous cytoprotective and antioxidant genes
It was absent in a higher percentage of beta cells than glucagon cells independent of disease or autoantibody positivity
