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It is not understood if the interaction of PML-II with the INM is direct, involves adaptor proteins or post-translational modifications (Figure 1) ( RNA-mediated silencing of PML-II in U2OS cells did not significantly affect total nLD abundance and size ( High resolution imaging of immunostained LAPS in U2OS cell revealed that CCT and PML occupy different regions of the LAPS and have minimal overlap

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Dissolve one portion in water, dilute to volume with water, and mix well to obtain the test solution

Proteomics 6 , 4153 (2006)

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