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Feedback preservation: The body's regulatory systems remain intact
The interactions between PD-L1 and PD-1 normally help prevent immune-mediated tissue damage upon activation
Consequently, episodes of tissue injury and incomplete healing of the intestinal epithelium are a prerequisite for immune reactivation and account for recurrent, chronically progressing phenotypes of IBD
Engineering the robustness of Saccharomyces cerevisiae by introducing bifunctional glutathione synthase gene
