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This is in contrast to most of other class A GPCRs, for which TM5 usually undergoes notable conformational changes at the cytoplasmic region during receptor activation 38

Oxidative stress is recognized as a key driver of endothelial damage and vascular stiffness, which are fundamental contributors to hypertension and other cardiovascular conditions [91]

Its origins in gastric juice hint at one of its most powerful roles: gut protection and healing

doi: 10.1016/0024-3205(91)90423-9

Our bodies naturally produce it, but they dont use it to synthesize protein, so taurine is considered a semi-essential (or conditionally essential) amino acid