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in vivo , whereas SLC7A11 / embryonic fibroblasts underwent cell death in routine culture medium in vitro but could proliferate normally in the presence of 2-mercaptoethanol (2ME), N-acetyl cysteine (NAC), or vitamin E (Stipanuk, 2004

Particularly, IGF-1, the major growth-stimulating hormone, is commonly involved in mechanisms of under- and overnutrition

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