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Yet, there remains uncertainty about the sequence and direction of events, i.e., which are upstream or downstream, and which may be hubs for intersecting spokes

doi: 10.1016/s0140-6736(97)11096-0

One of them, named ferroptosis, was first described in 2012 as a nonapoptotic, iron-dependent form of cell death

Proteotoxicity: an underappreciated pathology in cardiac disease

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