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As the information from other metabolites was available too (choline and creatine), this information was included for complementary purposes and allows comparability with previous observations (Rodrguez-Nieto et al., 2023)

HMOX1 is distinguished by a heme-binding pocket that is oriented toward the cytoplasmic lysate and includes a histidine imidazole moiety for binding to heme iron

Cancer chemoprevention: signaling pathways and strategic approaches

Wistar rats (55/sex per dose) were exposed for life (6 h/day, 5 days/week, for 28 months) to acetaldehyde concentrations of 1350, 2700, or 1800-5400 mg/m 3 (the last concentration was gradually reduced from 5400 mg/m 3 in week 20 to 1800 mg/m 3 in week 52)