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doi:10.2903/j.efsa.2011.2144
Thus, it seems logical that stressed erythrocytes should be cleared from circulation before hemolysis occurs to avert proinflammatory and highly detrimental lytic destruction

Interleukin-1 (Il-1) transcriptionally activates hepcidin by inducing ccaat enhancer-binding protein (C/ebp) expression in hepatocytes

These antibodies then attach to specialized immune cells called mast cells
