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Obesity drug sibutramine (Meridia): hypertension and cardiac arrhythmias

In Canada and most of the European Union, its not approved for medical or cosmetic use and is considered an unregulated compound (Health Canada advisory listing AOD9604 as unauthorized)

Injection-Related Considerations As with any injectable medication, proper technique and sterile handling are essential

However, the use of low doses of leptin to maintain weight loss attained by other anorectic medicines and lifestyle modifications is emerging as a pharmacotherapeutic option [39,40]

Omitting the EJ modifier causes the payer to treat each injection as the first in a new series, triggering quantity-limit denials on the second and third visits