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And, although the amount of weight lost was statistically significant, the average loss was 2.4 pounds (1.1 kg), not necessarily clinically significant

418-430 (Lippincott Williams & Wilkins).Google Scholar SONAIYA, E.B

A recent study suggested that plasma levels of 5-MT, a compound related to serotonin metabolism, may be decreased in CFS patients, but this has been interpreted as a confounder caused by serotonin-selective reuptake inhibitor (SSRI) use in these patients (40)

Moreover, a recent clinical study found that vitamin D at levels ~5 times greater (48 g) than that used in this report, had no effect on improving muscle strength in healthy older adults [56]
Studies in Crat knockout mice demonstrated that CrAT deficiency leads to abnormal fuel selection, which results in a perturbation of glucose homeostasis and suggest that deficits in CrAT activity might contribute to diet-induced metabolic inflexibility by exacerbating the Randle glucose-fatty acid cycle 66
