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This targeted delivery method allows for optimal absorption and utilization of biotin by hair follicles, promoting healthy hair growth and reducing hair loss

These changes promote cell apoptosis and ultimately lead to the death of motor neurons, contributing to the onset of ALS (116)

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Briefly, PE and PTC snap-frozen tissue was pulverized in liquid nitrogen and homogenized in RIPA buffer (150 mM NaCl, 50 mM Tris, 1% NP-40, pH 7.5)

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