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[20] For nutritional deficiency without intrinsic-factor loss, shorter courses-such as 30-100 mcg intramuscularly daily for five to ten days followed by 100-200 mcg monthly-are often sufficient

Cutting corners on supplies often leads to contamination, degradation, or inaccurate dosing

However, oral supplements often just arent enough

Insulin Resistance (with prolonged use) Paradoxically, while IGF-1 LR3 acutely improves glucose uptake, chronic high-dose use can promote insulin resistance as a compensatory mechanism

Related to vasodilation
