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2) fold-change of each ligand 2 compared to db/m mice
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Discussion The results of the present study showed that serosal application of acetic acid to induce gastric ulcer has resulted in gastric damage with elevated levels of pro-inflammatory cytokines along with increased neutrophil infiltration, lipid peroxidation, cyclooxygenases and prostaglandins, in conjunction with depleted antioxidant GSH in the gastric tissue

The solubility and absorption of different types of saponins can be improved by adding some absorption enhancers and improving the different dosage forms of the drug, such as nanoformulations, microemulsions, enteric dissolution, etc., or by applying nano-delivery systems to increase the permeability and to combat the gastrointestinal degradation, which can largely improve the bioavailability of PNS (Ruan et al., 2010

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