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Given that the cellular thiol network, including GSH, involves crosstalk between the cytosol and organelles, we selected two of the dysregulated enzymes, which had been identified by 2D electrophoresis, with important roles in mitochondrial function, i.e., Aco2 and mitochondrial creatine kinase (mtCK) (Fig

While proteomics measures hundreds of proteins in clinical samples, the complex data processing and interpretation remain a significant challenge 8,9

de Beeck, K

For studies requiring sustained peptide exposure, twice-daily dosing maintains more consistent plasma levels than single daily administration

Modulation of -glutamylcysteine synthetase large subunit mRNA expression by butylated hydroxianisole