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J Nat Prod 71:11131116 Matthew S, Paul VJ, Luesch H (2009) Tiglicamides AC, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides
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Consistently, NMR analysis revealed elevated levels of glutamine and serine, accompanied by decreased concentrations of the glutamic acid precursor -ketoglutarate in PD patients, while UPLC/MS analysis indicated a reduction in serum glutamic acid levels (Figs
This resulted in increased expression of proapoptotic proteins and vice versa, decreased expression of antiapoptotic proteins
