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It was only recognized in the late 1980s that desensitization of insulin secretion, which describes a state of decreased secretory responsiveness of -cell to the glucose stimuli, is a pathophysiological phenomenon of -cell function and not just an in vitro artifact 30

The intranasal administration of GHK-Cu represents a novel approach aimed at overcoming the challenge of bypassing the blood-brain barrier, a common hurdle in traditional targeted neurotherapeutics [14-16]

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The liposome wraps around the glutathione and keeps it protected from stomach acids and digestive enzymes during the whole journey