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Continuous activation of c-Met receptors without recovery periods may lead to receptor internalization and reduced surface expressiona protective mechanism cells employ when signaling pathways are overstimulated

This scenario is worsened by a decrease in the activities of superoxide dismutase and catalase, enzymes of the antioxidant defense, which result in impairment of the redox equilibrium contributing to altering the intestinal Ca 2+ absorption

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Though few people recognize its importance, glutathione ( gloota-THIGH- own ) is the most powerful antioxidant in our bodies

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