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Description
Sheybani, Natasha D
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Presently, isatuximab is approved for the treatment of RRMM in combined therapy with pomalidomide and dexamethasone [79] and, in patients who have undergone two prior therapies, in combination with carfilzomib and dexamethasone [80]
The transformation of AngIV and earlier described analogs into clinically useful agents has been impeded by their lack of metabolic stability and inability to penetrate the blood-brain barrier (BBB)
Capillaries allow the exchange of important substances, such as oxygen, with the surrounding tissues
