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Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces

2 Slowing of gastric emptying By slowing the rate at which food moves from the stomach to the small intestine, cagrilintide extends the sensation of fullness after meals and moderates the speed at which glucose enters the bloodstream

Prez-Torres I, Manzano-Pech L, Rubio-Ruz ME, Soto ME, Guarner-Lans V

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With a 2.4 mg dose of pemvidutide at week 48, a phase 2 obesity trial of pemvidutide (MOMENTUM 48-week trial) found a mean weight loss of 15.6%