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This synthesis process involves sequential catalysis by tyrosine hydroxylase (TH) and aromatic amino acid decarboxylase (AADC), which progressively convert tyrosine into dopamine (172)

Whether such benefit extends equally convincingly to other microvascular complications of diabetes like nephropathy and neuropathy will need to be explored in future dedicated research

However, one of the major metabolic alterations in cancer cells involves aerobic glycolysis, in which pyruvate is converted directly to lactate, generating less ATP than oxidative phosphorylation in normal cells

L.et al (2015a)

Sayyid et al., 2024), veliparib (Mizuno et al., 2023