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Agents targeting mutations in IDH1 mutations, such as AG-120 and FT-2102, and IDH2, such as AG-221 have shown promise in clinical trials, effectively lowering 2-HG levels, inducing cellular differentiation, and demonstrating clinical efficacy in patients with relapsed or refractory AML [23]

Basic and therapeutic aspects of angiogenesis

[DOI] [PubMed] [Google Scholar] 80.Kane N., Oware A
Recent advances in the surgical treatment of advanced gastric cancer: a review

doi: 10.3389/fimmu.2021.720109 146 KobayashiE
