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1991 European Food Safety Authority Panel on Dietetic Products, Nutrition, and Allergies

Obesity : Assists with weight loss and appetite control, particularly in individuals with obesity or overweight

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[DOI] [PubMed] [Google Scholar] 37.Hannibal L, Jacobsen DW

Summary: Metformin commonly reduces vitamin B12 levels by interfering with calcium-dependent absorption in the terminal ileum, particularly with long-term use and higher doses
