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It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system

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Cells were resuspended in 200 l 1:2 tert-butanol:water to prepare for the click reaction

Another short-term study used intravenous DSIP at 25 nmol/kg for 4 nights in chronic insomniacs

While epidemiological evidence indicates that this motor system disease is associated with poisoning from cyanogenic glucosides found in improperly processed cassava, not all individuals who rely on a cyanogenic diet are affected during outbreaks of konzo, suggesting additional and yet unknown factors required for onset of disease 4,5