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Contraindications include active liver disease and severe kidney impairment

Follow-up Repeat broad markers after 8-12 weeks if symptoms change or the protocol continues

Have a Gastrointestinal Disorder Individuals with gastrointestinal conditions such as Crohns disease or celiac disease may have difficulty absorbing adequate amounts of vitamin B12

Patients with liver diseases, such as fatty liver, hepatitis, or cirrhosis 7

Immunogenicity: No Antibody Formation A critical safety consideration for any peptide therapy is immunogenicity, the potential to trigger immune system responses that could lead to allergic reactions, reduced efficacy through antibody neutralization, or autoimmune complications