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Additional symptoms include impaired wound and fracture healing, easy bruising, and loose or decaying teeth

5-Amino-1MQ selectively inhibits nicotinamide N-methyltransferase (NNMT), a methyltransferase enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide

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Furthermore, ex vivo studies with venous leg ulcer exudates confirmed the inhibitory capacity of the dressings against myeloperoxidase and matrix metalloproteinase