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Methods: 2100 adults within 24 hours of stroke onset, moderate to severe neurological impairment (NIHSS10) or dysphagia and NIHSS6, without pneumonia at screening, contraindications to metoclopramide, pregnancy, and life-limiting comorbidities will be recruited from 60 or more UK hospitals

Messaging frequently fails to reach young people effectively, often being inaccessible or misaligned with motivations for appearance enhancement and creating a gap where experiential information sources dominate, they wrote

This approach has been very helpful in patients who have significant weight to lose, have plateaued in their efforts, or patients in whom the additional energy is beneficial to their life situation

this effect can be explained by an interaction with the cholinergic system[54]