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Both pathways are linked in some cell types by the cleavage of BID, a proapoptotic member of the Bcl-2 family of proteins, generating tBID in a process catalyzed by caspase-8 activated by the extrinsic pathways (Scaffidi et al., 1998)
Specifically, we highlight the latest breakthroughs in utilizing natural and dietary compounds as potent ferroptosis regulators
Curr Opin Clin Nutr Metab Care (2010) 13:5417
doi: 10.3389/fphar.2021.628988
Phenylbutyrate up-regulates the DJ-1 protein and protects neurons in cell culture and in animal models of Parkinson disease
