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This work is an example of how DTP cells can activate the same mechanism to promote both drug tolerance and immune evasion
Capsaicin exerts anti-tumor effects by inhibiting cancer cell proliferation, inducing cell cycle arrest, inhibiting tumor angiogenesis, and promoting cancer autophagy (Chakraborty et al., 2014
doi: 10.1042/BST20170503 [DOI] [PubMed] [Google Scholar] 402
This is achieved through the merging of the mitochondrial outer membrane and inner membrane mediated by GTPases Mfn1 and 2 (Mfn 1/2) and OPA1, respectively (Liu et al., 2020)
Synthesis of L-ascorbic acid in the phloem
