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doi: 10.1016/S0006-8993(01)02759-7

As emphasized, although not specifically investigated in the glaucoma rats, the recently described activation of the Src-Caveolin-1-eNOS pathway [103,104] and interaction with several molecular pathways [103,104,107,108,109,110,111,112,113,114,115] may be important for maintaining vasomotor tone, and thereby essential for prompt therapeutic effect in glaucoma rats

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Historically, assays have ranged from those using target cells with surface receptors that capture recombinant viral proteins and effector cell lines to those using virus-infected primary target cells and isolated effector cells from the same donor