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Description
In patients with CLL, the vast majority of NOTCH1 mutations affect the C-terminal PEST domain of the protein, impacting its ability to be ubiquitinated and degraded [14]
10.1016/j.jns.2008.12.010 J
Jeremias A, Soodini G, Gelfand E, Xu Y, Stanton RC, Horton ES, et al
Glutamine metabolism in cancers: targeting the oxidative homeostasis
The evidence-backed path to sustainable weight loss with GLP-1 centers on correct medication selection, appropriate dose titration, and behavioral supportnot supplement stacking
