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Another study followed the autoimmune protocol (AIP), which is a version of a Paleo diet

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Antisense oligonucleotide knockout FMO3 in mice reduced atherosclerosis, and downregulation of FMO3 not only reduced TMAO level but also regulated lipid metabolism and inflammation, thereby reducing atherosclerosis (Shih et al., 2015)

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Another study also found that acylcarnitine C3:0 was decreased in the end-stage renal disease (ESRD) with depression than those without depression and C3:0 had a good ability to diagnose depression in the ESRD (AUC = 0.934) (42)